Frequently used in humans, paracetamol, aspirin and ibuprofen cause each year many poisonings in dogs and cats. Read this article to understand the risks associated with inappropriate use of these drugs in dogs and cats.
Inappropriate self-medication and accidental ingestion of the owner of the drugs are common causes of poisoning in these three products.
(Reminder: The content of this article as that of other areas within the Vet Advice is registered and protected by the Copyright Any partial or total copy of it is prohibited For more information on sharing arrangements.. information that Tips Véto offers click here.)
Paracetamol in dogs and cats
Widely used as an anti-inflammatory drug in humans (Dafalgan®, Efferalgan®, Doliprane® for example, or in generic form), paracetamol regularly pose serious health problems in dogs and cats. It is also called acetaminophen (name that you will find if you go abroad).
Paracetamol toxicity in dogs and cats
Why this drug is toxic to dogs and cats so that man use it regularly?
In the case of paracetamol, an enzyme located in the liver to review its metabolism (processing path and drug in the body before they act or to be removed) is little present in dogs and absent in cats.
Indeed, paracetamol accumulates in the liver and triggers a chain reaction that destroys the liver cells and reaches then the blood by modifying the hemoglobin contained in red blood cells. One speaks of méthémoglobinisation resulting in a chocolate brown coloration of blood and a major defect in the transport of oxygen.
– High sensitivity. The absorption is less dangerous!
– The action is fast and takes only a few hours to put the liver in the roads and cause death!
– Paracetamol absolutely must not be given to cats.
– Dogs, meanwhile, are sensitive to overdose (fast for dog small size).
– Dog Death may also occur depending on the dose and the size of it!
– Strongly recommended in the dog, it will not be used (for lack of better) with the advice and the advice of a veterinarian and especially not in a dog with liver problems (liver)!
Symptoms of paracetamol poisoning (dogs and cats)
Symptoms, stronger and faster in cats are:
– Vomiting and called salivation salivation (damage of the stomach).
– Blood disorders: destruction of red blood cells (hemolytic anemia), which may jaundice, inefficient transport of oxygen linked to the méthémoglobinisation (brown blood).
– These most associated with liver failure (which usually detoxifies the blood) can lead in turn: edema, impaired coordination and seizures.
– Late evolution was hypothermia and death.
Rather violent when we know that the basic idea was to relieve a cat or dog!
aspirin acetaminophen ibuprofen chat aspegic
Jaundice (jaundice) in a cat intoxicated.
Treatment of acetaminophen poisoning (dogs and cats)
Action 1 to implement: call the vet (dealing or guard)! It is a vital emergency!
Depending on the situation and the distance to the clinic, the vet can give you directions to your pet vomit (useful in the 1st hour), give activated charcoal or antidote.
Luckily there is an antidote:
– The N-Acetyl-Cysteine found in products like Mucomyst® or Fluimucil®.
– Vitamin C is also involved in the treatment.
Only the veterinarian can determine the doses to be administered. Do not do anything and refer to him who alone can put the odds on the side of your pet!
Warning: The antidote is not enough! It is common to have to hospitalize the animal to induce vomiting, the infusion set, try to save his liver, according to oxygenate the need to practice and sometimes a transfusion. It also seeks to manage pain and discomfort.
paracetamol cat dog doliprane efferalgan daffalgan
Paracetamol poisoning can lead to hospitalization of your dog or cat
Even a dog and treated well, even more, a cat has serious risks of dying during this type of poisoning. If the liver is shot, it seems unlikely in the current state of veterinary medicine or another transplant!
Do not give acetaminophen to your pet and do not leave it lying around your medication! This is the best advice (and safest) I can give you!
Aspirin and ibuprofen in dogs and cats
Used to shovel in humans, aspirin (Aspégic®, Aspirin UPSA® generic aspirin) and ibuprofen (Advil®, Nurofen®, generic ibuprofen) are also responsible for frequent poisonings in dogs and cats . We process together because both drugs have the same mechanism of action explaining their toxicity.
Toxicity of aspirin and ibuprofen in dogs and cats
To understand the toxicity of these two molecules, look at how they work in animals.
In the body of the dog, cat and man, we find everywhere prostaglandins in the organs. These prostaglandins are (as hormones) small messengers that are produced through controlled chemical reactions by enzymes. Once created, prostaglandins activate specific body reactions, depending on their nature.
What interests us here are enzymes called cyclooxygenase (COX abbreviated) which enable the manufacture of certain prostaglandins involved in 2 ways in the body:
– Thanks to COX-1, release of prostaglandins which act on the basic functions. Those that interest us here, protecting the stomach and intestine, good blood circulation in the kidneys and action on platelets.
– Thanks to COX-2, release of prostaglandins which activate inflammation.
dog cat aspirin ibuprofen Advil nurofen aspegic
Action of aspirin and ibuprofen in dogs and cats
Used as anti-inflammatory drugs, aspirin and ibuprofen halt the operation of COX-2 but also, unfortunately, COX-1.
These two drugs work well to reduce inflammation (pain, redness, fever, …) but have lower side effects for the protection of the stomach against the acidity as well as protection of the bowel and decreasing the blood circulation in the kidneys.
To this is added an anti-platelet action that disrupts the good coagulation of blood in the body. This action is very active for aspirin and ibuprofen for transient and may cause abnormal bleeding.
These side effects occur at much lower doses for dogs and cats compared to humans. Again, the cat is much more sensitive than the dog!
Aspirin and ibuprofen should not be given to dogs and even less to cats without the advice of a veterinarian. Today there are anti-inflammatory effective and safer than your vet may prescribe.
Note: Veterinarians sometimes prescribe aspirin to cats and dogs. The indication in this case, is generally to limit the blood clots in the vessels (thrombosis) and thin blood with anti-platelet effect thereof. We see that for some heart trouble or when venous thrombosis in cats, for example. If your veterinarian has prescribed aspirin no worries! Self medication is banned by cons!
Symptoms related to aspirin and ibuprofen (dog and cat)
Symptoms of poisoning aspirin or ibuprofen arise from what has been explained above:
– Loss of appetite / Anorexia: This is often the first symptom.
– Vomiting and diarrhea.
– Digestive hemorrhages: ulcers in the stomach and intestinal bleeding that may cause the output black stools and / or accompanied by traces of blood.
– Abdominal pain.
– Bleeding in the rest of the body (decreased blood clotting) triggering depression, pale mucous membranes (eyes, gums …), respiratory problems.
If poisoning is strong or persists over several days:
– Renal impairment (kidney) and hepatic (liver): strengthening of previous symptoms + increased urination and thirst (called polyuria / polydipsia), possible jaundice (jaundice).
– Adverse central nervous system disorders of coordination, convulsions, coma.
– Death of the animal.
Processing on poisoning these 2 drugs (dog and cat)
As in the case of paracetamol, the first action is to call your veterinarian whose advice may save your pet. It is a vital emergency!
They can recommend, in the early hours only, to induce vomiting and / or give activated charcoal before bringing the dog or cat to the clinic.
During poisoning aspirin or ibuprofen, there is no antidote!
And the care are essential to cleanse the body, protect organs and support vital functions. Hospitalization is common and allows infusion-up addict animal. Hepatic and renal protective, gastrointestinal dressings, painkillers (against pain) and antibiotics are administered.
aspirin ibuprofen chat aspegic nurofen advil
Blood in a cat.
In the most severe cases, it may even be necessary to transfuse. Anemia can indeed be fatal when the blood loss (stomach, intestines, blood vessels from the body, …) are too large.
The death of the dog or cat may still be inevitable during heavy poisoning aspirin or ibuprofen.
Again, do not give aspirin or ibuprofen to your dog or cat without the advice or prescription of a veterinarian. This remains, once again, the best recommendation we can make you! Again, much safer molecules exist in veterinary pharmacopoeia.
So here you informed (e) serious risks to your dogs and cats if they absorb paracetamol, aspirin or ibuprofen. The toxicity discussed here, could lead to the death of your pet, should be enough to dissuade you to give them or let hang your medications.
Remember to share via your social networks link to this article with your friends and family with cats and dogs! This will surely make their service and avoid big problems in many animals.